HIV/AIDS Skepticism

Pointing to evidence that HIV is not the necessary and sufficient cause of AIDS

Archive for the ‘antiretroviral drugs’ Category

Intestinal dysbiosis hypothesis goes mainstream

Posted by Henry Bauer on 2017/05/20

It seems that the idea of recommending probiotics for “HIV+” people has become downright mainstream now. The following links were sent me by Tony Lance; they mention among other things dysbiosis and microbial translocation, which Tony had pointed to in his essay, cited on this blog nearly a decade ago (What really caused aids: slicing through the Gordian Knot).

“Impact of probiotic Saccharomyces boulardii on the gut microbiome composition in HIV-treated patients: A double-blind, randomised, placebo-controlled trial” by Judit Villar-García et al.

“Microbes & HIV” by Jeannie Wraight

“STUDY: Probiotic could help prevent disorders in people with HIV” by Jeannie Wraight.
This mentions “A new study reported in the International Journal of Molecular Sciences”, presumably “Probiotics differently affect gut-associated lymphoid tissue indolamine-2,3-dioxygenase mRNA and cerebrospinal fluid neopterin levels in antiretroviral-treated HIV-1 infected patients: A pilot study” by Carolina Scagnolari et al. [Int. J. Mol. Sci. 2016, 17(10), 1639; doi:10.3390/ijms17101639] .
This article was in a special issue of IJMS, “Immuno- and Neuropathogenesis of HIV Disease: Mechanisms, Prevention, Treatment, and Cure” which included another pertinent piece:

“Impact of HIV infection and anti-retroviral therapy on the Immune profile of and microbial translocation in HIV-infected children in Vietnam” by Xiuqiong Bi et al. [Int. J. Mol. Sci. 2016, 17(8), 1245; doi:10.3390/ijms17081245] .

Neither of those sources mentions the probiotic Visbiome, referred to in Wraight’s article. However, the Visbiome website  cites “Probiotic supplementation promotes a reduction in T-cell activation, an increase in Th17 frequencies, and a recovery of intestinal epithelium integrity and mitochondrial morphology in ART-treated HIV-1-positive patients” by Gabriella d’Ettorre et al. [Immunity, Inflammation and Disease, 2017; doi: 10.1002/iid3.160]  whose Conclusions are worth quoting:
“These findings highlight the potential beneficial effects of probiotic supplementation for the reconstitution of physical and immunological integrity of the mucosal intestinal barrier in ART-treated HIV-1-positive patients”.

 

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Posted in Alternative AIDS treatments, antiretroviral drugs, clinical trials, HIV in children | Tagged: , , | 6 Comments »

Quality of life when diagnosed HIV+ or AIDS

Posted by Henry Bauer on 2017/05/20

An obscure publication from Universidad Juan Agustín Maza (in Argentina) came to my attention via Research Gate:

“Iniciativas para mejorar la calidad de vida de personas con VIH positivo y SIDA: Revisión del Diagnóstico, el Pronóstico y la Terapéutica a la luz de la Ciencia y de la Ética” by M. E. Molina, J. Abou Medelej, S. Perez Daffunchio, D. E. Crisafulli & J. Álvarez.
[Initiatives to improve the quality of life of HIV-positive and AIDS-diagnosed patients: A review of diagnosis, prognosis, and therapy from viewpoints of science and ethics]

The full article is in Spanish with an Abstract in English:
“The first cases of AIDS occurred in 1981. There are not fully appropriate therapeutic interventions for treating this medical condition yet. People who are diagnosed with positive HIV or AIDS suffer a poor quality of life and receive medication that produces severe adverse reactions. The purposes of this investigation are: * To review the existent reports on the etiology, diagnosis, prognosis and treatment of HIV. * To bring the affected people updated information for healthcare and improvement of their quality of life. We have analyzed a significant number of papers published in several countries on these topics, and we have found the following inconsistencies: * HIV risk behaviors: According to the CDC in the United States, the Estimated Per-Act Probability of Acquiring HIV from an Infected Source, by Exposure Act (heterosexual) is about one in one thousand for woman, and about one on two thousands for man. Nevertheless, an investigation conducted through the University of San Francisco, California, on 442 discordant heterosexual couples no seroconversion was observed throughout the ten years the research lasted. (1985-1995). * Diagnostics methods: In Argentina, we employ the ELISA screening method, posteriorly confirmed by a western blot test, but in the United Stated this last is discouraged since 2014. * Medication: The drugs that are used to treat HIV are DNA chain terminators which interfere with the normal functioning and replication of normal cells. As a result, damage in the immune system and the mitochondrial DNA are reported. We wonder what should we inform the patients and people in general about all these. We require the experts´ opinion on the ethical management aspects. Due that the diagnostic tests employed may result in false positives, and the fact that the medication is highly toxic, we recommend that patients with HIV positive diagnosis re-test their condition at least once a year”.

This all seems quite sound, but after citing false positives, no sexual transmission, and the toxicity of ARVs the last sentence is quite a let-down.

The mention of vaccines is also a mixture of sound and doubtful:[Google translation]:
Regarding the possible development of vaccines.
The difficulty in developing vaccines due to HIV mutation has been explained: the high coding error rate produced by the reverse transcriptase enzyme and the recombination of various phenotypes of HIV in the DNA of infected cells (Montagnier L., 2008). However, other retroviruses that respond to the same replication mechanisms do not produce mutations that impede the development of vaccines. Example: Murine Leukemia Virus. Likewise, a purification of up to 20% of HIV has not been reported to date, so doubts remain about the specificity of antibodies used in diagnosis (Leung, Hans Gelderblom Extended Interview min 37.48) , 2011”

Evidently the authors accept HIV/AIDS theory but are puzzled by its internal contradictions.

 

Posted in antiretroviral drugs, experts, HIV tests, HIV transmission, Legal aspects, sexual transmission, vaccines | Tagged: | 15 Comments »

Countering the conventional wisdom

Posted by Henry Bauer on 2017/05/09

Individuals who have looked at primary evidence about HIV and AIDS have invariably concluded that HIV is not the cause of AIDS. That evidence is quite clear in the primary research literature, see for example the >900 citations in THE CASE AGAINST HIV.

Honest journalists recognize what the facts are, and some of them have written excellent books about the matter. One such book is Positively False by Joan Shenton, who has also filmed and archived a number of informative documentaries.

In the face of the facts, the official position of authoritative institutions remains that HIV causes AIDS, and the mass media help to enshrine this as the conventional wisdom. One consequence is that many individuals and many organizations who have no acquaintance with the primary evidence try to suppress those like Shenton who persist in drawing attention to the damage that HIV=AIDS dogma brings to countless people via the highly toxic, indeed quite deadly “antiretroviral” drugs.

Shenton’s latest  documentary, Positive Hell, “is a 30-minute documentary that tells the stories of five Spanish people, living in northern Spain, who tested positive for HIV in the late 80s who, defying the overwhelming medical consensus, chose not to take medication …”.  Widely praised and nominated for awards, some announced screenings were canceled because of pressure from “AIDS charities” and ignorant individuals. An outline of these acts of censorship has now been posted by the Index on Censorship.  Well worth reading.

Posted in antiretroviral drugs, HIV skepticism, HIV tests, unwarranted dogmatism in science | Tagged: , , | 1 Comment »

Why do gay men test “HIV-positive” more frequently than others?

Posted by Henry Bauer on 2017/03/29

AIDS was first noticed and described among gay men.

In 1984, it was concluded, officially but mistakenly, that AIDS was caused by HIV.

That AIDS is not caused by HIV follows from innumerable pieces of evidence (The Case against HIV http://thecaseagainsthiv.net), for example that the incidence of AIDS does not correlate with instances of “HIV-positive” (1).
Why then do gay men test “HIV-positive” more often than others?

That is of more than academic interest. If there is some inherent connection between HIV and gay men, and since AIDS is inextricably connected historically to gay men, the two connections reinforce the mistaken conventional wisdom that HIV causes AIDS.

Well: Do gay men really test “HIV-positive” more often than others?

According to the Centers for Disease Control & Prevention, “Gay and bisexual men are more severely affected by HIV than any other group in the United States. From 2005 to 2014, HIV diagnoses decreased in the United States by 19% overall, but increased 6% among all gay and bisexual men … . Gay, bisexual, and other men who have sex with men made up an estimated 2% of the population but 55% of people living with HIV in the United States in 2013. If current diagnosis rates continue, 1 in 6 gay and bisexual men will be diagnosed with HIV in their lifetime, including 1 in 2 black/African American gay and bisexual men, 1 in 4 Hispanic/Latino gay and bisexual men, and 1 in 11 white gay and bisexual men” (“HIV Among Gay and Bisexual Men” [Page last updated: September 30, 2016] ).

In New Zealand, it is claimed that 1 in 15 gay and bisexual men are “HIV-positive” (New Zealand AIDS Foundation, “Three reasons gay guys are more likely to get HIV”) — the three reasons given include anal sex and the statistical likelihood of having sex with “HIV-positive” men.

A survey of global data for the years 2007-2011 reported (2) relative rates of “HIV-positive” for gay men as compared to all adults, in different regions of the world, showing consistently higher prevalence among gay men; once again the authors suggest that the greater likelihood of transmitting HIV by anal sex is the reason.

But since we know that HIV is not sexually transmitted (see section 3 in The Case against HIV), what could be the real reason for this disparity?

When greater incidence of “HIV-positive” among gay men is cited in terms of numbers found to be positive, one can suspect that it is because gay men are more likely to be tested in the first place; but no such explanation in terms of sampling bias can be invoked when the disparity appears to be in relative rates.

We know also that positive “HIV” tests are not proof of the presence of the purported retrovirus HIV; and we know that innumerable physiological circumstances may produce a “positive” result on an HIV test, see sub-section 3.2.2 in The Case against HIV). Those circumstances include many types of infections and ailments, as well as some conditions that are not ill health , say pregnancy or vaccinations, or some quite non-specific indications of perhaps quite minor threat to health, say oxidative stress.

It is not easy to see, however, why any or all of those “false positives” should be more common among gay men across cultures and regions. Perhaps anal sex, with possible tissue damage and transfer of semen, could induce release of substances reflective of physiological stress. Where antibody “HIV” tests yield an indeterminate result, it is known that heterosexual men and women tend to be reported as negative but gay men as positive. Perhaps too there is a nocebo effect: gay men have been indoctrinated to worry about “getting HIV”, and such worry is likely to be greatly exacerbated when anticipating or undergoing testing. Perhaps social persecution has also brought on average a higher rate of anxiety and somehow unhealthy living among gay men.

No combination of those possibilities seems adequate to explain the reported variations in rates, however. Moreover, as to anal sex, it is unlikely in the extreme that this is in itself notably dangerous to health: humans have been practicing anal sex for millennia, and if it were a significant risk to health, that would surely have been noticed very long ago.

Could it be that there is a biological, genetic basis for a tendency toward homosexuality? That suggestion has been ventured at times, albeit without convincing proof coming to hand as yet (3).

It is quite certain, though, that the tendency to test “HIV-positive” is strongly determined by genetics: the relative rates of testing “HIV-positive” are universally race-associated (chs. 5 & 6 in [1]), and substances taken to be characteristic of HIV are characteristic of commonly occurring human endogenous retroviruses, HERVs (4).

I find it amazing that mainstream researchers venture hand-waving non-explanations (5) for the much greater incidence of “HIV-positive” among African Americans than among white Americans, even though “risky” behavior is less among African Americans, and national rates of “HIV-positive” are highest in countries with a large proportion of people of African ancestry, namely Africa and the Caribbean. The Centers for Disease Control & Prevention has published innumerable data showing persistent and consistent variations by race, for instance (above) the rates of 1 in 11 for white Americans, 1 in 4 for Hispanics, and 1 in 2 for black Americans.

But the most likely reason why gay men test “positive” is also a major reason for the “AIDS” illnesses and deaths in the early years: INTESTINAL DYSBIOSIS; search this blog for all the posts describing this condition and confirming the plausibility of this hypothesis.

Why all this matters so much

The continuing refrain in the media about the prevalence of “HIV-positive” among gay men reinforces the mistaken notion that “HIV-positive” is dangerous to health, in particular that it presages overt illness, AIDS, and death. At the very least this strengthens the force of the mainstream dogma and makes it more difficult to present the Rethinking case. Very likely it exerts a nocebo effect that itself contributes to poor health.

It needs to be said, shouted, over and over again:

“HIV-positive” does not mean definitely ill, it does not mean infected by HIV, and anyway HIV doesn’t cause AIDS. Anyone, gay or not, who is told they are “HIV-positive”, should consult a physician who is not indoctrinated into HIV=AIDS, see Rethinking AIDS Medical Professional List.

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  1. Henry H. Bauer, The Origin, Persistence and Failings of HIV/AIDS Theory, McFarland 2007.
  2. Chris Beyrer, Stefan D. Baral, Frits van Griensven, Steven M. Goodreau, Suwat Chariyalertsak, Andrea L. Wirtz & Ron Brookmeyer (2012). “Global epidemiology of HIV infection in men who have sex with men”, The Lancet,  380 (9839) 367-77.
  3. Brian P. Hanley (2011). “Dual-gender macrochimeric tissue discordance is predicted to be a significant cause of human homosexuality and transgenderism”, Hypotheses in the Life Sciences, 1 #: 63-70.
  4. Etienne de Harven (2010). “Human endogenous retroviruses and AIDS research: Confusion, consensus, or science?”, Journal of American Physicians and Surgeons, 15: 69-74.
  5. Gregorio A. Millett, John L. Peterson, Stephen A. Flores, Trevor A. Hart, William L. Jeffries 4th, Patrick A. Wilson, Sean B. Rourke, Charles M. Heilig, Jonathan Elford, Kevin A. Fenton & Robert S Remis (2012). “Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA: a meta-analysis”, The Lancet, 380 (9839): 341-8.

Posted in antiretroviral drugs, HIV and race, HIV as stress, HIV does not cause AIDS, HIV risk groups, HIV skepticism, HIV tests, HIV transmission, HIV/AIDS numbers, sexual transmission, uncritical media | Tagged: | 5 Comments »

Larry Kramer in Love and Anger

Posted by Henry Bauer on 2017/01/30

Larry Kramer in Love and Anger is a 2015 HBO documentary. It recounts most of the history of AIDS through Kramer’s personal involvement and it is largely accurate in what it discusses, though omitting and ignoring some crucial points.

Watching it brought home to me once again what an enormous tragedy this has been and still is and will continue to be because the ultimate crux remains unaccepted: namely, that “science” including medical science can go wrong, and that there are no systemic safeguards against that, no checks or balances, because minority voices within the scientific community are not attended to, instead are castigated and persecuted.

This film gives a good account of the fear that spread among gay men as a mysterious syndrome of illnesses was bringing deaths, several hundred thousand in about half-a-dozen years. But the film also misses the opportunity to make the case against HIV, despite some significant clues. Thus Kramer’s 1978 novel, Faggots, is correctly described as his jeremiad against the fast-lane lifestyle that included much health-damaging use of “recreational” drugs. The film might well have been pointed out that this preceded the appearance of AIDS and could indeed explain why so many people became very ill — as some of them recognized, for instance Michael Callen and his physician Sonnabend. Again, Kaposi’s sarcoma (KS) is mentioned as a characteristic AIDS disease, but the film neglects to point out that KS virtually dropped out of the picture after some years as insightful gay men abandoned the use of the nitrite inhalants (“poppers”) that cause this damage to blood vessels (“AIDS KS” is probably different from the classic KS.)

Completely missing is the tragic story of how HIV came to be the accepted cause of AIDS, essentially by declaration at a press conference before any scientific publication.

Kramer’s initiatives are properly credited for revision of the FDA’s procedures for approving drugs — but missing is a discussion of the damaging consequences, not only because of the toxicity of AZT and later “anti-retroviral” drugs but because the fast-track approval system is now abused routinely by Big Pharma to bring to market avalanches of new drugs that reveal their toxicity within a short time after marketing: note the TV and print announcements by lawyers about class-action suits against such medications as Pradaxa, Xeralto, Invokana, and others at the very same time as the drug companies continue to advertise those drugs with dishonest descriptions of potential benefits (“remission is possible”, for example) and down-playing of “side” effects, for instance in TV ads showing healthy actors instead of actual patients actually on the drugs.

The film applauds the introduction of protease inhibitors, but fails to describe their toxicities, again despite obvious clues. Thus the film opens and closes with Kramer in hospital after a liver transplant; and there is a short clip of Kramer warning earlier about the side effects of his medications. The New York Times review of the film of course says, misleadingly, “liver transplant necessitated by his H.I.V. infection” instead of “made necessary by the anti-retroviral medication including protease inhibitors”: “Drug-induced hepatitis and hepatic decompensation (and rare cases of fatalities) have been reported with all PIs” (Table 14, Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents, 8/8/2014).

And of course nothing is said about dissent from HIV/AIDS theory.

So this documentary can serve only as a reminder of the tragic history of AIDS. I realized also how the nature of the tragedy has changed. Initially it was the mis-identification of the cause as HIV and the subsequent hundreds of thousands of deaths from AZT. But nowadays this has been compounded by the abuse of HIV tests as proof of infection, whereby no sector of society is free from the danger of mis-diagnosis and subsequent mistreatment. Since pregnancy seems to stimulate positive “HIV” tests, especially with women of African ancestry, women and their fetuses and babies are being harmed in significant numbers and will continue to be until the HIV/AIDS blunder is corrected.

For the facts about HIV and AIDS, see The Case against HIV. For why HIV cannot be the cause of AIDS, and the story of how the error was made and entrenched, read The Origin, Persistence and Failings of HIV/AIDS Theory [Jefferson (NC): McFarland 2007].

Posted in antiretroviral drugs, clinical trials, HIV does not cause AIDS, HIV risk groups, HIV tests, HIV/AIDS numbers, uncritical media | Tagged: , | 1 Comment »