AIDS Rethinking was again disseminated to mainstream researchers, this time at the 65th Annual Congress of the Italian Society for Anatomy and Histology in Padua, 27-29 September 2011.
An extensive poster presentation (authors: Ruggiero, Pacini, Punzi, Morucci, Gulisano, Köhnlein, Bauer) discussed “The Clinical Significance of Immune-System Laboratory Tests”. The poster makes the following salient points:
→ Scientists accept conclusions of experts in fields outside their own specialties. The resulting mainstream “consensus” can remain unchanged for a long time even after the experts have modified or discarded their earlier conclusions.
→ That is so with HIV/AIDS, where evidence has accumulated that the original hypothesis was wrong:
♦ Kaposi’s sarcoma is not caused by HIV.
♦ Many clinical AIDS cases were found to be HIV-negative
(and renamed — entirely ad hoc — “idiopathic CD4-T-cell lymphopenia”).
♦ Anti-retroviral drugs often cause clinical deterioration instead of
helping patients recover (“immune restoration syndrome”).
Patients on Highly Active Anti-Retroviral Therapy (HAART)
experience more adverse non-AIDS events than AIDS events.
♦ “HIV” tests are anything but specific; false-positives arise from a host of conditions
that are not necessarily health-threatening.
♦ CD4 counts are not a good biomarker of clinical condition, nor a criterion of illness,
still less a reason for instituting HAART.
→ Treating manifest illnesses has a better record of good patient outcomes than does antiretroviral treatment.
→ CD4 counts can be increased quickly and safely by means of probiotic dietary supplements.
[The poster is available for download but takes appreciable time because of its size, ~32 MB as jpg and ~50 MB as pdf]
Expanding on the question of CD4 counts and probiotics, Pacini, Punzi, Morucci, Ruggiero, & Cheney presented a study entitled “Macrophages of the Mucosa-Associated Lymphoid Tissue (MALT) as key elements of the immune response to vitamin D binding protein-macrophage activating factor (GcMAF)”:
→ Probiotic yogurt has been shown to increase CD4 counts in people living with HIV/AIDS.
→ The results were not replicated with encapsulated probiotics, suggesting the need for an additional factor. GcMAF has been found to act as such a factor.
→ Increased CD4 counts under such a regimen have been demonstrated recently in several control subjects, in an HIV-positive patient, and in two individuals affected by chronic fatigue syndrome.
→ Natural Killer (NK) cell counts increased as well as CD4 counts and CD4/CD8 ratio. The significance is that NK cells influence the quality of immune responses, are associated with the clinical prognosis for “HIV-positive” patients, and play a major role in HIV elite controllers.
→ There were also favorable changes in hematological parameters indicative of bone-marrow function, and there was significant improvement in general health.