HIV/AIDS Skepticism

Pointing to evidence that HIV is not the necessary and sufficient cause of AIDS

Posts Tagged ‘Nessies’

Circumcision pseudo-science

Posted by Henry Bauer on 2009/09/02

The possible benefits and drawbacks of male circumcision have been argued over for decades, centuries, probably millennia. The coincidence that a procedure originating as a religious ritual should turn out to have beneficial, health-protective side-effects is by no means impossible, though no one argues that case for the religious ritual of female circumcision. What’s clear is that medical opinion has been and continues to be divided [David L. Gollaher, “From ritual to science: the medical transformation of circumcision in America”, Journal of Social History, 28 #1 (1994) 5-36]:
“Ironically, but predictably in the context of the history of medical arguments for circumcision, some doctors have conjectured that removing the foreskin may protect men from the most dreaded epidemic of the post-modern world: the human immunodeficiency virus (HIV). Using retrospective data (the epidemiological equivalent of empiricism) from a venereal disease clinic in Kenya, for example, researchers observed that there were higher rates of HIV infection in the home communities of uncircumcised than circumcised men. Ignoring racial, ethnic, and sociocultural variables — the chief factors dictating whether or not an African boy is circumcised in the first place — they hypothesized that circumcision might serve to inhibit the transmission of the AIDS virus. One wonders whether this theory will endure. But within a medical community desperate to find some weapon against AIDS, its appeal is understandable. Even a physician who is a sober skeptic of the methodologies behind such studies allows that they ‘do suggest that HIV may be more infective during heterosexual intercourse if the male partner is uncircumcised and has a mucosal or cutaneous ulcer.’ [77] AIDS, the nemesis of modern science and medicine, remains a mystery. By some equally mysterious process, it is surmised, circumcision may help”.
[77: Simonsen et al., “Human Immunodeficiency Virus infection among men with Sexually Transmitted Diseases: Experience from a Center in Africa,” NEJM 319 (1988) 274-8; Cameron et al., “Female to male transmission of Human Immunodeficiency Virus Type I: Risk factors for seroconversion in men,” Lancet 2 (1989) 403-7; Marx, “Circumcision may protect against the AIDS virus,” Science, 245 (1989) 470-1; Poland, “The question of routine neonatal circumcision,” NEJM, 322 (1990) 1312-5”]

It is worth noting that circumcision as a way of avoiding becoming “HIV-positive” was mooted already in the late 1980s, and enthusiasts have continued to pursue definitive evidence for that for some two decades, despite contraindications no less probative than the pro-indications: a number of studies have found circumcision to be NOT associated with a lower rate of “HIV-positive”; see, for example, those cited in “Rwanda: Circumcise all men — even if it means more ‘HIV’ ‘infection’” [3 February 2008].

I’ve commented before on the remarkable similarities between HIV/AIDS and topics often labeled pseudo-science [“Science Studies 102: Burden of proof, HIV/AIDS ‘science’, pseudo-science”, 22 July 2008;  “HIV/AIDS and parapsychology: science or pseudo-science?”, 30 December 2008;  “Mainstream pseudo-science good, alternative pseudo-science bad”, 25 February 2009]. The failure after two decades of effort to find conclusive proof that circumcision prevents “HIV-positive” is somewhat reminiscent of decades of enthusiastic seeking of evidence for the reality of UFOs or the existence of Nessies; though one might have imagined, perhaps naïvely, that it might be easier to observe circumcision and frequency of “HIV-positive” than to investigate objects like UFOs or Nessies that cannot be brought under observation on command. Still, as Scientific Explorers like to say, “absence of evidence is not evidence of absence”.

At any rate, two decades of observational studies have been inconclusive as to whether there is an association between circumcision and “HIV-positive” status. A recognized problem is the number of potentially confounding factors in these observational studies, primarily cultural and religious characteristics that are often correlated with genetic characteristics.

A powerful argument that CIRCUMCISION DOES NOT PROTECT against “HIV-positive” status comes from solid and consistent observational data on cohorts of gay men. Universally, the groups most frequently testing “HIV-positive” are drug abusers and gay men; in the official jargon, injecting drug users (IDU) and men who have sex with men (MSM). Since IDU are supposedly infected via needles that do not normally make contact with the foreskin, MSM are the group most at risk for acquiring “HIV-positive” status via the foreskin; therefore this would be the ideal group for detecting any preventive effect of circumcision. But a review of 18 such studies found no preventive effect of circumcision against “HIV-positive” among MSM: Millett et al., “Circumcision status and risk of HIV and sexually transmitted infections among men who have sex with men”, JAMA, 300 [2008] 1674-84.

How then does it come about that the HIV/AIDS Establishment has accepted as an article of faith that circumcision reduces by half the risk of becoming “HIV-positive”? For example,

“CDC mulls routine circumcision of infants to reduce spread of HIV” (Tracy Miller, 25 August 2009)
“In an effort to reduce the spread of the AIDS-causing HIV virus, the Centers for Disease Control are currently mulling routine circumcision for all baby boys born in the United States . . . . The controversial recommendations, scheduled for a formal release by the end of the year, come on the heels of research that shows circumcised men in African countries hit hard by AIDS had half the risk of getting infected as those who were uncircumcised.
Critics say that focusing on newborns in the United States would only have an effect years down the road, and that circumcising infants subjects them to medically unnecessary surgery without their consent.
But CDC experts maintain that any step to reduce the spread of HIV is worthy of serious consideration.
‘We have a significant H.I.V. epidemic in this country, and we really need to look carefully at any potential intervention that could be another tool in the toolbox we use to address the epidemic,’ Dr. Peter Kilmarx, chief of epidemiology for the CDC’s division of HIV/AIDS prevention, told the Times. ‘What we’ve heard from our consultants is that there would be a benefit for infants from infant circumcision, and that the benefits outweigh the risks.’
Experts acknowledge that a new circumcision policy is unlikely to have a dramatic effect in HIV infection rates, as most adult men are already circumcised. Additionally, scant evidence exists to prove circumcision protects homosexual men from getting HIV.
79 percent of adult American men are already circumcised, according to public health statistics, though circumcision of newborns has dropped to about 65 percent in recent decades” [emphases added].

Note the usual bureaucratic prevarications:
— Unnamed “experts” and “consultants” are cited in the attempt to outweigh the actual scientific evidence;
— “a significant H.I.V. epidemic” is asserted to exist in the USA, contrary to fact;
— however, insofar as there may be an appreciable frequency of  “HIV-positive” instances in the USA, a large proportion is among MSM, who have been found NOT to benefit in this respect from circumcision;
— and that fact is euphemized or obfuscated by saying “scant evidence exists” instead of that the evidence speaks clearly against any benefit from circumcision.

Note too, “on the heels of research”: It is elementary that new research is not to be relied on until it has been confirmed over time by independent investigators and in a variety of circumstances. This rush to judgment is junk science. REAL SCIENCE ISN’T NEWS [Scientific illiteracy, the media, science pundits, governments, and HIV/AIDS, 15 January 2009].

Since HIV/AIDS theorists do not hesitate to swallow absurdities wholesale, they do not blink at the suggestion that “While circumcision may help protect heterosexual men in Africa from contracting HIV, . . .  it does not appear effective in doing so for American gay men, according to the largest study yet on the issue. . . . Circumcision ‘is not considered beneficial’ for gay men concerned about lowering their risk of becoming infected with HIV, Dr. Peter Kilmarx of the CDC told the Associated Press. He released the study findings at a conference on Tuesday. . . . But circumcision may not offer the same protection when it comes to anal sex, Kilmarx said.” [“Circumcision won’t shield gay men from HIV: Study” ].
Here once more the HIV/AIDS gurus would like to swing both ways, or perhaps every way. On the one hand, it is an hoary shibboleth that gay men are particularly at risk because anal sex is more conducive to “HIV transmission” than is vaginal sex, because of a greater likelihood of skin breakage and blood contact. But in order to justify a program of universal circumcision, it becomes expedient to take somehow the opposite view.

Why would circumcision be preventive?
“Scientists think circumcision can protect against HIV because the tissue of the foreskin has a high number of target cells for HIV infection and is susceptible to tearing during intercourse, providing an entry point for the virus” [“Circumcision: Change in medical opinion possible”].
But, again, anal sex is supposed to pose a greater risk for tearing skin than does vaginal sex. “I also find it fascinating that the male prepuce has gone straight from being an inconsequential ‘flap of skin’ to being a complex immunological organ, just in time to be infected by a virus that targets immune cells” [Winkel, “Rush to judgment”, PLoS Medicine 3(1) (2006) e71].

So the official conclusion is not only highly implausible, it is contrary to the facts accumulated over some twenty years or so. Yet all that is jettisoned by reliance on 3 brand-new clinical trials in Africa, all of them stopped prematurely after a year, that have supposedly shown definitively that circumcision reduces by about 50% the risk of becoming “HIV-positive” — among African heterosexual men, that is, though not among American gay men [Gray et al., “Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial”, Lancet, 369 (2007) 657-66; Bailey et al., “Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial”, ibid., 643-56; Auvert et al., “Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 trial”, PLoS Medicine 2(11) (2005) e298].
A detailed deconstruction of these reports has to be deferred to a later post, this one is already longer than I prefer, but at least one feature of them is readily cited and adds greatly to the implausibility of the conclusion drawn:
In all three trials — in South Africa, Uganda, and Kenya —, the purported effect of circumcision was essentially the same at 50-60%, and it was independent of all other observed variables, among them number of sexual partners, non-marital relationships, condom use, paying for sex, drinking alcohol before sex, age, marital status, education (so stated specifically in Gray et al.).
Think about that. The probability of acquiring any sexually transmitted infection must depend on the probability of intercourse with an already infected person, which itself depends on the prevalence of the infection in the population; also influential will be the number of acts of intercourse and the number of partners, and whether sex is “social” or paid for, because prostitutes are by shibboleth supposed to be a reservoir of HIV and STDs; important too must be the care taken to protect via condoms, which is supposedly influenced by the state of sobriety or lack of it. Yet in 3 different cultures, in 3 widely separated regions of Africa, with groups of different age ranges, and where the incidence of “HIV-positive” in the control groups differed  significantly, somehow all those variables turn out to balance one other so precisely that the overall effect of the studied treatment is almost exactly the same. This strikes me as about as likely as 2 blue moons in the same year, or as Nessie surfacing just as I’m greeted by an alien emerging from a landed UFO.

There is quite a good reason, actually, why all 3 studies should have delivered the same apparent effect of circumcision, but it has nothing to do with “HIV” or sexual transmission: Surgery is well known to suppress immune function. Now the standard test for “HIV” is actually a test for antibodies, and the evidence is ample that “HIV” tests are highly non-specific, reacting “positive” when large numbers of a variety of antibodies are present. Since post-operative antibody production is lower as a consequence of surgery, post-operative apparent “HIV” incidence will be lower.

These clinical trials have demonstrated only that surgery cuts by about half (50-60%) the production of non-specific antibodies.

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Believing and disbelieving

Posted by Henry Bauer on 2009/07/03

(This is a long post. HERE is a pdf for those who prefer to read it that way).

“How could anyone believe that?” is a natural question whenever someone believes what is contrary to the conventional wisdom, say, that HIV doesn’t cause AIDS, or that Loch Ness monsters are real animals.

Since the role of unorthodox views in and out of science has been the focus of my academic interests for several decades, I had to think about that question in a variety of contexts. My conclusion long ago was that this is the wrong question, the very opposite of the right question, which is,

“How does anyone ever come to believe differently than others do?” (1)

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It’s a widespread illusion that we believe things because they’re true. It’s an illusion that we all tend to harbor about ourselves. Of course I believe what’s true! My beliefs aren’t wrong! It’s the others who are wrong.

However, we don’t acquire beliefs because they’re true, we acquire them through being taught that they’re true. For the first half-a-dozen or a dozen years of our lives, before we have begun to learn how to think truly for ourselves, as babies and children we almost always believe what parents and teachers tell us. Surely that has helped the species to survive. But no matter what the reason might be, there’s ample empirical evidence for it. For instance, many people during their whole lifetime stick to the religion that they imbibed almost with mother’s milk; those who reject that religion do so at earliest in adolescence.

That habit of believing parents and teachers tends to become ingrained. Society’s “experts”  — scientists and doctors, surrogate parents and teachers — tend to be believed as a matter of habit.

So how do some people ever come to believe other than what they’ve been taught and what the experts say?

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I was prompted to this train of thought by receiving yet again some comments intended for this blog and which were directed at minor details, from people whom I had asked, long ago, to cut through this underbrush and address the chief point at issue: “What is the proof that HIV causes AIDS?”

Whenever I’ve asked this of commentators like Fulano-etc.-de-Tal, or Chris Noble, or Snout, or others who want to argue incessantly about ancillary details, the exchange has come to an end. They’ve simply never addressed that central issue.

And it’s not only these camp followers. The same holds for the actual HIV/AIDS gurus, the Montagniers and Gallos and Faucis. Fauci threatens journalists who don’t toe the orthodox line. Gallo hangs up on Gary Null when asked for citations to the work that made him famous.

Why can’t these people cite the work on which their belief is supposedly based?

Finally it hit me: Because their belief wasn’t formed that way. They didn’t come to believe because of the evidence.
The Faucis and Gallos came to believe because they wanted to, because a virus-caused AIDS would be in their professional bailiwick, and they were more than happy to take an imperfect correlation as proof of causation.
The camp followers came to believe simply because they were happy to believe what the experts say and what “everyone else” believes. Who are they to question the authority of scientific experts and scientific institutions?

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To question “what everyone knows”, there has to be some decisive incentive or some serendipitous conjunction. I’ll illustrate that by describing how I came to believe some things that “everyone else” believes and some things that “everyone else” does not believe.

The first unorthodox opinion I acquired was that Loch Ness monsters are probably real living animals of some unidentified species. How did I come to that conclusion?
Serendipity set the stage. Reading has been my lifelong pleasure. I used to browse in the local library among books that had just been returned and not yet reshelved, assuming that these would be the most interesting ones. Around 1961, I picked from that pile a book titled Loch Ness Monster, by Tim Dinsdale. I recall my mental sneer, for I knew like everyone else that this was a mythical creature and a tangible tourist attraction invented by those canny Scots. But I thumbed the pages, and saw a set of glossy photos: claimed stills from a film! If these were genuine . . . . So I borrowed the book. Having read it, I couldn’t make up my mind. The author seemed genuine, but also very naïve. Yet his film had been developed by Kodak and pronounced genuine. Could it be that Nessies are real?
I was unable to find a satisfactory discussion in the scientific literature. So I read whatever other books and articles I could find about it. I also became a member of the Loch Ness Investigation, a group that was exploring at Loch Ness during the summers, and I followed their work via their newsletters — I couldn’t participate personally since I then lived in Australia.
A dozen years later, on sabbatical leave in England, I took a vacation trip to Loch Ness. More serendipity: there I encountered Dinsdale. Later I arranged lecture tours for him in the USA (where I had migrated in 1965). Coming to know Dinsdale, coming to trust his integrity, seeing a 35mm copy of his film umpteen times during his talks, brought conviction.
It had taken me 12-15 years of looking at all the available evidence before I felt convinced.

The unorthodox view that underwrites this blog is that HIV doesn’t cause AIDS. How did I come by that belief in something that “everyone else” does not believe?
More serendipity. Having concluded in the early 1970s that Nessies were probably real, I became curious why there hadn’t been proper scientific investigations despite the huge amount of publicity over several decades. That led eventually to my change of academic field from chemistry to science studies, with special interest in heterodoxies. So I was always on the lookout for scientific anomalies and heresies to study. In the mid-1990s, I came across the book by Ellison and Duesberg, Why We Will Never Win the War on AIDS (interesting info about this here ; other Ellison-Duesberg articles here).
Just as with Dinsdale’s book, I couldn’t make up my mind. The arguments seemed sound, but I didn’t feel competent to judge the technicalities. So, again, I looked for other HIV/AIDS-dissenting books, and wrote reviews of a number of them. Around 2005, that led me to read Harvey Bialy’s scientific autobiography of Duesberg. For months thereafter, I periodically reminded myself that I wanted to check a citation Bialy had given, for an assertion that obviously couldn’t be true, namely, that positive HIV-tests in the mid-1980s among teenage potential military recruits from all across the United States had come equally among the girls as among the boys. The consequences of checking that reference are described in The Origin, Persistence and Failings of HIV/AIDS Theory.
As with Nessie, it had taken me more than ten years of looking into the available evidence to become convinced of the correctness of something that “everyone else” does not believe.

So am I saying that I always sift evidence for a decade before making up my mind?
Of course not. I did that only on matters that were outside my professional expertise.

Studying chemistry, I didn’t question what the instructors and the textbooks had to say. I surely asked for explanations on some points, and might well have raised quibbles on details, but I didn’t question the periodic table or the theory of chemical bonding or the laws of thermodynamics or any other basic tenet.

That, I suggest, is quite typical. Those of us who go into research in a science don’t begin by questioning our field’s basic tenets. Furthermore, most of us never have occasion to question those tenets later on. Most scientific research is, in Kuhn’s words (2), puzzle-solving. In every field there are all sorts of little problems to be solved; not little in the sense of easy, but in the sense of not impinging on any basic theoretical issues. One can spend many lifetimes in chemical research without ever questioning the Second Law of thermodynamics, say, or quantum-mechanical calculations of electron energies, and so on and so forth.

So: Immunologists and virologists and pharmacologists and others who came to do research on HIV/AIDS from the mid-1980s onwards have been engaged in trying to solve all sorts of puzzles. They’ve had no reason to question the accepted view that HIV causes AIDS, because their work doesn’t raise that question in any obvious way; they’re working on very specialized, very detailed matters — designing new antiretroviral drugs, say; or trying to make sense of the infinite variety of “HIV” strains and permutations and recombinations; or looking for new strategies that might lead to a useful vaccine; and so on and so forth. Many tens of thousands of published articles illustrate that there are no end of mysterious puzzles about “HIV/AIDS” waiting to be solved.

The various people who became activist camp followers, like the non-scientist vigilantes among the AIDStruth gang, didn’t begin by trying to convince themselves, by looking into the primary evidence, that the mainstream view is correct: they simply believed it, jumped on the very visible bandwagon, took for granted that the conventional view promulgated by official scientific institutions is true.

It is perfectly natural, in other words, for scientists and non-scientists to believe without question that HIV causes AIDS even though they have never seen or looked for the proof.

What is not natural is to question that, and the relatively small number of individuals who became HIV/AIDS dissidents, AIDS Rethinkers, HIV Skeptics, did so because of idiosyncratic and specific reasons. Women like Christine Maggiore, Noreen Martin, Maria Papagiannidou, Karri Stokely, and others had the strongest personal reasons to wonder about what they were being told: since they had not put themselves at risk in the way “HIV” is supposedly acquired, and since they were finding the “side” effects of antiretroviral drugs intolerable, the incentive was strong to think for themselves and look at the evidence for themselves.
Many gay men have had similar reason to question the mainstream view, and some unknown but undoubtedly large number of gay men are living in a perpetual mental and emotional turmoil: on one hand much empirical evidence of what the antiretroviral drugs have done to their friends, on the other hand their own doctors expressing with apparent confidence the mainstream view. So only a visible minority of gay men have yet recognized the failings of HIV/AIDS theory.
One of the first to do so, John Lauritsen, was brought to question the mainstream view for the idiosyncratic personal reason that, as a survey research analyst, he could see that the CDC’s classification scheme was invalid.
Among scientists, Peter Duesberg recognized some of the errors of HIV/AIDS theory because he understood so much about retroviruses and because he had not himself been caught up in the feverish chase for an infectious cause of AIDS. Robert Root-Bernstein, too, with expertise in immunology , could recognize clearly from outside the HIV/AIDS-research establishment the fallacy of taking immunedeficiency as some new phenomenon. Other biologists, too, who were not involved in HIV/AIDS work, could see things wrong with HIV/AIDS theory: Charles A. Thomas, Jr., Harvey Bialy, Walter Gilbert, Kary Mullis, Harry Rubin, Gordon Stewart, Richard Strohman, and many others who have put their names to the letter asking for a reconsideration.

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To summarize:

Mainstream researchers rarely if ever question the basis for the contemporary beliefs in their field. It’s not unique to HIV/AIDS. HIV/AIDS researchers and camp followers never cite the publications that are supposed to prove that HIV causes AIDS for the reason that they never looked for such proof, they simply took it for granted on the say-so of the press-conference announcement and subsequent “mainstream consensus”.

The people who did look for such proof, and realized that it doesn’t exist, were:
—  journalists covering “HIV/AIDS” stories (among those who wrote books about it are Jad Adams, Elinor Burkett, John Crewdson, Celia Farber, Neville Hodgkinson, Evan Lambrou, Michael Leitner, Joan Shenton);
—  directly affected, said-to-be-HIV-positive people, largely gay men and also women like those mentioned above;
—  individuals for a variety of individual reasons, as illustrated above for John Lauritsen and myself;
—  scientists in closely related fields who were not working directly on HIV/AIDS.

That last point is pertinent to the refrain from defenders of HIV/AIDS orthodoxy that highly qualified scientists like Duesberg or Mullis are not equipped to comment because they have never themselves done any research on HIV or AIDS. But that’s precisely why they were able to see that this HIV/AIDS Emperor has no clothes — scientists working directly on the many puzzles generated by this wrong theory have no incentive, no inclination, no reason to question the hypothesis; indeed, the psychological mechanism of cognitive dissonance makes it highly unlikely that scientists with careers vested in HIV/AIDS orthodoxy will be able to recognize the evidence against their belief.
More generally, this is the reason why the history of science contains so many cases of breakthroughs being made by outsiders to a particular specialty: coming to it afresh, they are not blinded by the insider dogmas.

So there is nothing unique about the fact that the failings of HIV/AIDS theory have been discerned by outsiders and not by insiders, and that the insiders are not even familiar with the supposed proofs underlying their belief. Nor is it unique that the dogma has many camp followers who never bothered to look for the supposed proofs of the mainstream belief. What is unique to HIV/AIDS theory is the enormous damage it has caused, by making ill or actually killing hundreds of thousands (at least). The annals of modern medicine have no precedent for this, which is another reason why thoughtless supporters of HIV/AIDS orthodoxy may feel comfortable with it despite never having sought evidence for it.

So here’s the question to put to everyone who insists that HIV causes AIDS:

HOW  DID  YOU  COME  TO  BELIEVE  THAT?
WHAT  CONVINCED  YOU?

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Cited:
(1) Henry H. Bauer, Beyond Velikovsky: The History of a Public Controversy, University of Illinois Press, 1984; chapter 11, “Motives for believing”.
(2) Thomas S. Kuhn, The Structure of Scientific Revolutions, University of Chicago Press, 1970 (2nd ed., enlarged; 1st ed. 1962)

Posted in experts, HIV does not cause AIDS, HIV skepticism, prejudice | Tagged: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | 10 Comments »