Cervical cancer — An update to “HPV Insanity”
Posted by Henry Bauer on 2014/03/25
After posting “HPV insanity”, I had asked some technically competent people for comments on the press release touting lopinavir as a cure for “HPV infection”. That brought a highly informative albeit also highly technical article (McCormack et al., Individual karyotypes at the origins of cervical carcinoma”, Molecular Cytogenetics, 6 [2013 ] 44.) in which actual cases of cervical cancer were successfully classified — independently of HPV infection or non-infection — by degree of disturbance of the cell’s chromosomes (aneuploidy, as opposed to the normal diploid state of paired chromosomes).
Peter Duesberg was one of the leaders of the erstwhile and unsuccessful search for human-cancer-causing viruses, and of the subsequent switch to considering activation of “oncogenes” as responsible for cancer. He has more recently been studying the possible role of aneuploidy, a condition in which cells acquire an abnormal complement of chromosomes: “Chromosomal chaos and cancer”, Scientific American, May 2007, 53-9.