HIV/AIDS Skepticism

Pointing to evidence that HIV is not the necessary and sufficient cause of AIDS

Intestinal dysbiosis theory confirmed again

Posted by Henry Bauer on 2011/04/28

A key aspect of intestinal dysbiosis theory  has been confirmed: Re-establishment of healthy gut microflora can lead to an apparent defeat of “HIV infection” — an increased CD4 count.

AIDS originally manifested as 3 diseases: candidiasis (thrush; yeast infections), Pneumocystis carinii pneumonia (PCP), and Kaposi’s sarcoma (KS).
Given that many KS patients are HIV-negative, it has been acknowledged for many years now, even by HIV/AIDS cultist, that Kaposi’s sarcoma is not caused by HIV. A sufficient explanation for the prevalence of KS in the early 1980s, and its increasing rarity since, is that it was caused by excessive use of nitrite poppers (see Death Rush by John Lauritsen & Hank Wilson).
It had not been recognized at first that PCP, like candidiasis, is a fungal infection (and it has been renamed Pneumocystis jiroveci, but I shall continue to use “PCP” since that has been so long and widely used and recognized).
An adequate explanation for the outbreak of AIDS in the early 1980s is the “fast-lane” lifestyle of a small proportion of gay men as part of the irrational exuberance that followed the apparent “gay liberation” of the 1970s: these men were sleeping little and partying much, sharing and spreading the common sexually transmitted diseases, treating those frequent infections with lots of antibiotics, even consuming antibiotics promiscuously as prophylactics (see for example the 2003 TV documentary, When Ocean Meets Sky). Dr. Josef Sonnabend, whose practice in New York included many gay men, predicted even in the 1970s that this lifestyle would lead to a breakdown of health. It did.
But why specifically yeast and PCP? Why specifically fungal diseases?
In conjunction with the hypothesis of intestinal dysbiosis, Tony Lance  pointed out that certain aspects of and practices associated with the fast-lane gay lifestyle seem as if designed to damage the intestinal microflora that constitute the first line of defense established by the immune system, a defense that acts particularly to hold in check fungal organisms that are ubiquitous.

The notion that HIV causes AIDS is disproved by many types of evidence. But that still leaves a conundrum: Why do gay men even nowadays so often test “HIV-positive”? Even gay men who remain in good health for decades without antiretroviral treatment?
Lance suggested that the damage to gut microflora would allow translocation from the gut to the blood of a variety of substances that might cause reactions that could manifest as responding positive on “HIV” tests. That suggestion has been confirmed in recent years as a significant number of mainstream articles have acknowledged an important role for the gut microflora as part of the immune system, and that damage to this mucosal immune-system allows translocation and “immune activation” — the latest hand-waving term that substitutes for a specific mechanism by which “HIV” is supposed to cause damage.

CD4 counts and viral load are the standard measures for inferring the course that “HIV infection” is taking: higher CD4 or lower viral load means the “infection” is being successfully controlled. Now it has been found that probiotic treatment, helping a healthy gut microflora re-establish itself, leads to higher CD4 counts and to a decrease in immune activation — to controlling “HIV infection”, in other words, without recourse to antiretroviral drugs:

Clerici et al., “Nutritional intervention with NR100157 restores gut microbiota in HIV-1-infected adults not on HAART and reduces systemic immune activation”, 18th Conference on Retroviruses  and Opportunistic Infections (Boston, MA,  February 27 — March 2, 2011):
“Background: A compromised gastrointestinal tract can contribute via microbial translocation to the persistent chronic immune activation observed in HIV-infected individuals. Previously, the nutritional concept NR100157 containing prebiotic oligosaccharides was shown to reduce CD4+ T cell decline in HIV-1-infected adults, in the double-blind placebo controlled BITE trial, after 52 weeks intervention. This was associated with decreased immune activation in a subpopulation. . . .
Conclusions: This study shows that nutritional intervention with NR100157 beneficially affects the gut microbiota composition in HIV-1-infected adults. Microbiota changes correlated with CD4+CD25+ T cell changes in a subgroup analysis, implying positive effects of NR100157 on intestinal homeostasis and systemic immune activation.”

About these ads

13 Responses to “Intestinal dysbiosis theory confirmed again”

  1. mo79uk said

    It’s looking ever more likely that the Terrence Higgins Trust will have to be renamed the Tony Lance Foundation. :)

  2. Marcus Vonsant said

    Dr. Bauer,
    It seems to me to be a bit far reaching to make the statement that this single study “confirms Intestinal Dysbiosis theory”. The study you linked showed improvement in bifidobacteria and decreasing of Eubacterium rectale-Clostridium coccoides cluster as a direct result of a nutritional supplement. The improvement of CD4 and CD25 TCells was a great result, but hardly a confirmation of Lance’s theory. Also, there are many other species of bacteria in the gut that this study does not address.

    Lance’s theory was only for a very specific, subset of gay men who douched many times per day and many times per week, especially with a “Super Shot Douche” that Lance spoke of. However, this super-douche would not reach the entire colon, specifically the ascending & transverse colon where most of the gut flora resides. Also, Lance’s theory can hardly be attributed to the many other people who do not use these crazy devices.
    M. Vonsant

    • Henry Bauer said

      Marcus Vonsant:
      Douching, and especially the Power Shot douche is only an extreme example, and instructive in that it can explain why gay men who are particularly concerned to behave in a healthy way may nevertheless become HIV+ and sometimes even ill. The intestinal dysbiosis theory explains why in the 1980s the small proportion of gay men participating in the fast-line life came down specifically with opportunistic fungal infections. How is the theory not confirmed when rebuilding the intestinal microflora turns out to increase CD4 counts, the chief mainstream measure of “HIV disease”? The point is that HIV/AIDS theory is not required to explain these results, they are adequately handled by Lance’s hypothesis.

  3. Marcus Vonsant said

    If you claim that increasing the CD4 counts confirms ID in this instance, then how is it that ARVs, which greatly increase CD4 as well as greatly decrease viral load, do not confirm and validate HIV as the cause of the decrease in CD4 count? Especially when you consider that each class of HIV targets a specific pathway of HIV such as specific enzymes? It seems as if you want it both ways.
    M. Vonsant

    • Henry Bauer said

      Marcus Vonsant:
      I didn’t say that the study disproves HIV/AIDS theory. That HIV doesn’t cause AIDS is amply proved by all sorts of facts, for example the epidemiology analyzed in my book; and then there’s the fact that “HIV” tests don’t detect HIV; and much else on this blog and elsewhere.
      Further, anti-retroviral drugs don’t necessarily increase CD4 counts, hence the continual changing of the official NIH Treatment Guidelines and their reference to “immunological failure” of treatment; and in the HAART era, the median age of death of people being treated remains in the mid-40s — irrespective what the drugs do to CD4 counts, they don’t lead to a better clinical prognosis.
      You should read my blog in the context that the “HIV causes AIDS theory” has been disproved quite independently of anything to do with intestinal flora. That left the conundrum of what caused the original 1980s AIDS, and the intestinal dysbiosis hypothesis (together with the fact that poppers cause Kaposi’s sarcoma) is the best so far offered explanation for that.
      “AIDS” since the mid-1980s is a different animal altogether because of the manner in which the CDC definition of it has been changed. For about a decade, AZT treatment of HIV-positive people caused “AIDS” and usually death. Since the mid-1990s, various components of HAART are likely causes of illness in people who began “treatment” on teh absis of “HIV” tests and CD4 counts while clinically asymptomatic.

  4. Marcus Vonsant said

    First of all, I never said that you claimed the study “disproves HIV/AIDS theory”. I said that by your logic that the study you cite proves the Intestinal Dysbiosis theory, then all the studies that DO show a definite increase in CD4 and decrease in Viral Load as a direct result of ARVs, then those studies should prove that HIV decreases CD4 and increases Viral Load due to the highly specific aspects of ARVs. It is simply a matter of applying your stated logic to other equally logical (or more logical) statements; i.e. ARVs improve CD4 and VL.

    HIV tests do not test for HIV because it is too expensive and time consuming to isolate the virus itself, although isolation has been done eventhough you have claimed on this blog that it has not. (You see, I have read this blog.) HIV tests detect HIV antibodies which are highly specific. As you know, antibodies are not a general immunological phenomona. They are specific to the antigen to which they respond. That is why vaccines are so incredibly effective.

    I will not even address the “epidemiology of your book” since you do not cite specifics.

    Also, poppers do NOT cause KS. That is silly. No causation for that statement exists in any peer reviewed study.

    Lastly, the statement that HAART does not improve clinical outcomes is also a non supported statement. I know you say you disagree, but I wonder if you are being truthful with yourself and your readers.
    MV

    • Henry Bauer said

      Marcus Vonsant:
      “Also, poppers do NOT cause KS. That is silly. No causation for that statement exists in any peer reviewed study.”
      Read Lauritsen’s “Death Rush” and look “at the sources cited there. Look at the more recent review articles by Haverkos.

      “I said that by your logic that the study you cite proves the Intestinal Dysbiosis theory, then all the studies that DO show a definite increase in CD4 and decrease in Viral Load as a direct result of ARVs, then those studies should prove that HIV decreases CD4 and increases Viral Load due to the highly specific aspects of ARVs. It is simply a matter of applying your stated logic to other equally logical (or more logical) statements; i.e. ARVs improve CD4 and VL.”

      Now that IS silly.
      If I say that X can increase Y, and a study shows that, then my hypothesis is confirmed, quite irrespective of any other hypothesis about what anything else might be alleged to do to Y. If you want to suggest another hypothesis, that Z can increase Y, you then need to also cite studies that agree with that. As I remarked before, the literature is replete with accounts of “immunological failure”, i.e., that HAART failed to increased CD4 counts.

      “HIV tests do not test for HIV because it is too expensive and time consuming to isolate the virus itself, although isolation has been done even though you have claimed on this blog that it has not. (You see, I have read this blog.)”
      But you evidently have not read my citation of “Laboratory detection of human retroviral infection” by Stanley H. Weiss and Elliott P. Cowan, Chapter 8 in AIDS and Other Manifestations of HIV Infection, ed. Gary P. Wormser, 4th ed. (2004); nor apparently have you bothered to check that source for yourself. It says quite plainly that there is no gold-standard test for HIV, and that there is no test for HIV that is capable of diagnosing HIV infection. That’s because there has never been isolated the pure authentic HIV required for a gold-standard test. There is no other reason for the lack of a gold-standard test.

      “HIV tests detect HIV antibodies which are highly specific.”
      You haven’t read the sources cited on this blog and in my book about the numerous confounding reactions.

      “As you know, antibodies are not a general immunological phenomona. They are specific to the antigen to which they respond. That is why vaccines are so incredibly effective.”
      No, many antibodies are non-specific. Please cite a source for your assertion.

      “I will not even address the “epidemiology of your book” since you do not cite specifics.”
      I can’t summarize a whole book for you. I’m not telling you to buy it, get it from a library. I can’t discuss these things with people who don’t bother to look at the data I collected, all from mainstream sources. My book includes quoting a letter from the CDC to the effect that my data collation is sound and the trends I discern are really there.

      “Lastly, the statement that HAART does not improve clinical outcomes is also a non supported statement.”
      I’ve often cited the NIH Treatment Guidelines which state that the majority of adverse events experienced by people on HAART are non-AIDS events. Read those Guidelines and look at the “side” effects they enumerate. And ponder the fact that those Guidelines are “updated” more than annually.

  5. Martin said

    Hi Dr. Bauer, I saw the comments by Marcus Vonsant. Smells like a mole to me. Seth Kalichman perhaps? Who knows? A long time ago, back in the late 80′s, I read an interview with Peter Duesberg in of all places Spin Magazine. That interview suddenly made everything about AIDS obvious. It’s not a matter of “can not” for Vonsant and others like him (her?), it’s a matter “will not”.

    • Henry Bauer said

      Martin:
      Yes, possibly a mole; or a typically uninformed groupie.
      But things need to be continually repeated, because many people weren’t aware of these things in the 1980s — I don’t think I was myself. Spin Magazine was not mass media!

  6. Martin said

    Hi Dr. Bauer, actually Spin was national mass media in competition with Rolling Stone. Bob Guccione Jr. son of Penthouse publisher Bob Guccione. On the other hand John Lauritsen’s books and articles weren’t. Fortunately the local Gay book store (in Boston) run by John Mitzel.carried dissident AIDS literature both books and Contuum Magazine. Also because I was gay, I had a more than passing interest.

    • Henry Bauer said

      Martin:
      Thanks! There are huge areas of popular culture, very much including popular music, about which I’m totally ignorant.

  7. ale said

    interesting article in 1966
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935501/

    • Henry Bauer said

      ale:
      An illustration of what Rethinkers have pointed out from the beginning, that the actual manifest diseases of “AIDS” were not new, occurring for instance in infants with genetically caused immune deficiencies.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

 
Follow

Get every new post delivered to your Inbox.

Join 109 other followers